Kite will succeed Teri Schwartz in the new year.
The renowned director and playwright will depart at the end of the 2019-20 season.
The first woman to manage the $55 million Center Theatre Group offers tips on how to raise money for innovation.
Manfredi, a former assistant managing director with the Colorado company, will begin the post in the new year.
Clowdus, who founded the company in 2009, is onto a new venture: Brian Clowdus Experiences.
Pugliese, who first joined the company in 2013, will depart at the end of the month.
Following the appointment of Russell Granet as president and CEO, a number of women have been hired or promoted to leadership positions.
After the resignation of artistic director Burgess Clark due to sexual misconduct allegations, executive director Toby Schine has also stepped down.
The former artistic director of Syracuse Stage, and August Wilson aficionado, will take over the Silicon Valley company.
The co-founding leader of Ithaca’s Civic Ensemble prepares to take the helm of the similarly community-minded HartBeat Ensemble in Connecticut.